22. Skype - what we use to record our show
21. Twitter - to collaborate with people on the spot
20. Headphones -In your office so you can listen to things without everyone hearing it. With a mic if you need to record screencasts or podcasts.
19. Dropbox - a place to store all your documents online so you can access them anywhere anytime:)
18. Double monitors - Tutorials or having your email visible at all times.
17.Google Reader - or any of kind of RSS reader)
16. Netbook/portable laptop Macbook (Hackintosh!)
15. Evernote - Capture, scan, store pictures of whiteboards, search for anything
14. scanner - Fujutisu Scansnap for scanning to Evernote
13. Tweetie - Best iPhone twitter client - fast simple, easy to use (Tweetie 2 just came out) Melinda uses Echofon
12. Jing - Free screencast software for 3 min. tutorials (or Screenr or ScreenToaster for online or ScreenFlow)
11. Wiki - Document storage or Smart notebook storage.
10. Picture printer - (Kodak or HP or Epson PictureMate)
9. Flip video camera/digital - (upload to YouTube or Vimeo  or blip.tv or...)
8. iPod - so you can listen to our podcast of course!
7. Remember the Milk - Manage tasks, projects from desktop, iphone SMS, twitter
6. Google apps - for collaboration ( Google docs)
5. Google syncing - The ability to sync calendars, tasks, to your smartphone
4. Delicious - Now has an iPhone app
3. Tweetdeck - Desktop client to run twitter, has multiple columns to view as much as you need.
2. Instapaper - saving things to read when you have time:)
1. iPhone - It changed our lives (OK, Scott really didn't want me to say that but SERIOUSLY!)