Environmental Physiology
Starting 2010 course will be offered in the FallMWF 9:30-10:20 FSH 109
T 1:30-4:20 FTR 129 (lab - 5 credit only)
Official Website (enrollment required)
https://catalysttools.washington.edu/workspace/sr320/2395
For more information please
email instructor: Dr. Steven Roberts
Course Description:
Both freshwater and
marine environments are continually changing in response to both natural
processes and human activities, putting stress on aquatic organisms from
microbes to marine mammals. This course will explore the surprising
similarities and unique differences in the physiological response organisms
have to stress caused by factors as natural as tidal cycles, and as unnatural
as excess pharmaceuticals. The course will take an integrative approach across
disciplines linked to physiology, with an emphasis on molecular physiology and
endocrinology; and assumes students have been introduced to basic physiological
concepts in other coursework. The main focus will be on functional responses to
system stressors; however, the course will also explore potential impacts
at the population level, and the evolutionary implications of
physiological response to environmental stress. Case studies and research
papers will be used along with a primary textbook. The laboratory for this
course will involve student working cooperatively to develop research projects.
50 word description: Comparative advanced aquatic physiology course focusing on the functional response of organisms to natural and human-associated environmental stress. Lecture, laboratory work and team-based research project. Highly recommended: FISH324 or other introductory physiology course.
Course Goal: To provide upper level physiology course that focuses on aquatic
organisms and incorporates topics that students have limited exposure
to: endocrinology, sensory physiology, stress physiology, molecular mechanisms. In addition,
provide unique laboratory setting that promotes independent thought and
skills required to effectively work in groups.
Class Format:
Each class will start with a description some form or stress (usually in dramatic fashion), followed by the physiological response of a diverse range of taxa; microbes, shellfish, fish, amphibians. Mammalian physiology will be introduced sometimes for comparison. Content will come from text, research articles, and popular press. Discussions and interactive activities will be incorporated.
Lab Format:
Lab will take a goal-oriented approach driven by small groups of students. The projects will fall within the general theme of stress proteins (HSPs). Students will be able to design and carry-out an experiment selecting from certain taxa. Methodologies covered will include tissue sampling, nucleotide and protein extraction, SDS-PAGE, Western transfers and immunoblots, oxygen consumption monitoring, ELISAs, and microscopy.
For more details about the lab including student notebooks see:
http://genefish.wikispaces.com/FISH441
Anonymous Student Comments:"It
was interesting to see that when I was preparing to present the results
of the project how much of what I had learned throughout the quarter
applied to discussing the results. I think it actually sunk in! I was
excited about the comfort level I felt being able to discuss the
project."
What contributed most?"the
questions Steven asked us in class, may it be straightforward questions
to test our memory on what we have already learned, or questions with
unknown answers / no correct answers."
"Lab
section is key to the class. I'm very happy I decided to take both the
lecture and lab - more tools for the toolbox ... woo hoo!
"I
really like the discussions - especially when they helped support what
we had learned -- these are better discussions then typically happen in
class"
"Great textbook. One of the most readable texts. The lab was the valuable component."
Primary Textbook: Animal Physiology: from Genes to Organisms. Sherwood, Klandorf and Yancey. 2005 Brooks/Cole
Schedule of topics
Lecture Title (focus)
|
| Course Concepts, Review Cell Biology |
| Stress in the cellular environment (Housekeeping) |
| Stress in the cellular environment (Membrane Physiology) |
| Fluid and Acid-Base Balance (Osmoregulation) |
| Environmental Perception (Sensory Physiology) |
| When things go bad: Warming (Thermal Physiology) |
| Holiday |
| When things go bad: Plastics and Pharmaceuticals (Toxicology & Reproduction) |
| When things go bad: Organic Compounds (Epigenetics) |
| When things go bad: No Oxygen (Respiratory Physiology) |
| EXAM |
| Fishermen and Farmers: Fear (Adrenocorticotropic Physiology) |
| Fishermen and Farmers: Nets and Hands (Physical Stress) |
| Sex: Finding the right one (Pheromone, Spawning) |
| Sex: Production (Fertilization, Development) |
| Social Interactions: Family (Kin recognition, Quorum Sensing) |
| Social Interactions: Peers and Predators (Behavior) |
| Metamorphosis: Big taxa (Smoltification, Amphibians, Development) |
| Holiday |
| Metamorphosis: Small taxa (Microbes, Shellfish, Development) |
| Death and Dieing (Senescence, Aging) |
| EXAM |
| Disease (Large-Scale Processes) |
| Pathogen Virulence: Why are some so bad? (Virulence) |
Immune System: (Cell Signaling, Innate Immunity)
|
| Immune System: (Aquired Immunity) |
| Applications: Bio-indicators |
Presentations
|
Presentations
|
| Review |
Bookmark this page as:
tinyurl.com/FISH441